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Scientific Studies that prove the male sexual
enhancement power
of the herb Tongat Ali
The following scientific study abstracts document the aphrodisiac
qualities of
Tongkat Ali are reported on the website
http://www.ncbi.nlm.nih.gov of the
National Library of Medicine, National Institutes of Health, U.S. Public
Health Service.
Tongkat Ali Review by Dr. Simon Chua, Department of
Pharmaceutical Sciences,
Wayne State University, USA
In a preliminary study at the Reproductive Research Center in Kuala Lumpur,
Malaysia, 30 married men, aged 31-52 years old, took Tongkat Ali regularly
for three consecutive weeks. Interviews indicated that 48% felt healthy,
active and energized, and 40% felt increased sexual desire. The subjects
showed an increased free testosterone index. Increased testosterone levels
help improve libido, energy and muscle mass for body building. Their levels
of DHEA, another critical steroid hormone, gradually increased from 26%
after one week to 47% after three weeks. Most of the Tongkat Ali research
study subjects demonstrated
increased satisfaction in their sexual health and performance. In addition,
animal studies have shown that Tongkat Ali may increase testosterone
availability as well as libido in mice (Source: Article from the book
Molecular Biology of the Cell, published on Sept. 1, 2002).
Effects of Eurycoma longifolia Jack (Tongkat Ali) on the
initiation of sexual performance of inexperienced castrated male rats.
Ang HH,
Cheang HS,
Yusof AP.
School of Pharmaceutical Sciences, University Science Malaysia, Penang,
Malaysia, as reported in
Exp Anim.
2000 Jan;49(1):35-8.
We studied the effects of Eurycoma longifolia Jack, commonly known as
Tongkat Ali in Malaysia, on the initiation of sexual performance and the
weights of sexual accessories in inexperienced castrated male rats. The
doses of 200, 400 and 800 mg/kg body weight, which were extracted from E.
longifolia Jack, were orally administered to the rats twice daily for 10
days prior to the tests and continued throughout the test period.
Testosterone was used as a positive control after injecting 15 mg/kg daily
subcutaneously for 32 days. Results showed that E. longifolia Jack produced
a dose-dependent increase in sexual performance of the treated animals, but
the E. longifolia Jack groups showed lower sexual performance in mounting,
intromission and ejaculation than the testosterone group. Further results
also showed that E. longifolia Jack promoted the growth of both ventral
prostate and seminal vesicles as compared with the control, but the growth
of sexual accessories at 800 mg/kg of butanol, methanol, water and
chloroform fractions of E. longifolia Jack was less than that of
testosterone treated group. The present study therefore gives further
evidence of the folkuse of E. longifolia as an aphrodisiac.
PMID: 10803359 [PubMed - indexed for MEDLINE]
Evaluation of the potency activity of aphrodisiac in
Eurycoma longifolia Jack.
School of Pharmaceutical Sciences, University Science
Malaysia, Minden, 11800, Penang, Malaysia.
hhang@usm.my, as reported in
Phytother Res.
2001 Aug;15(5):435-6.
The butanol, methanol, water and chloroform extracts of
the roots of Eurycoma longifolia Jack were studied using various tests of
potency of treated male rats. The results showed that E. longifolia produced
a dose-dependent, recurrent and significant increase in the episodes of
penile reflexes as evidenced by increases in quick flips, long flips and
erections of the treated male rats during the 30 min observation period.
These results provide further evidence that E. longifolia increases the
aphrodisiac potency activity in treated animals. Copyright 2001 John Wiley &
Sons, Ltd.
PMID: 11507738 [PubMed - indexed for MEDLINE]
Eurycoma longifolia Jack enhances
libido in sexually experienced male rats.
School of Pharmaceutical Sciences, University of
Science Malaysia, Penang, Malaysia, as reported
in
Exp Anim.
1997 Oct;46(4):287-90.
The effects of Eurycoma longifolia Jack were studied on
the libido of sexually experienced male rats after dosing them with 200, 400
and 800 mg/kg body weight twice daily of different fractions of E.
longifolia Jack for 10 days. Results showed that E. longifolia Jack produced
a dose-dependent increase in mounting frequency of the treated animals with
400 mg/kg of chloroform, methanol, water and butanol fractions resulting in
mounting frequencies of 5.3 +/- 1.2, 4.9 +/- 0.7, 4.8 +/- 0.7 and 5.2 +/-
0.1, and 800 mg/kg further increased them to 5.4 +/- 0.8, 5.4 +/- 0.8, 5.2
+/- 0.6 and 5.3 +/- 0.2 respectively but there were no erections,
intromissions, ejaculations or seminal emissions during the 20-min
observation period which allowed for the measurement of sexual arousal
reflected by mounting frequency uninfluenced by other behavioural
components. This study provides evidence that E. longifolia Jack is a potent
stimulator of sexual arousal in sexually vigorous male rats in the absence
of feedback from genital sensation.
PMID: 9353636 [PubMed - indexed for MEDLINE]
Effects of Eurycoma longifolia Jack on sexual qualities
in middle aged male rats.
School of Pharmaceutical Sciences, University Science
Malaysia, Minden, Penang, Malaysia.
hhang@usm.my, as reported in
Phytomedicine.
2003;10(6-7):590-3.
The effects of Eurycoma longifolia Jack were studied on
the sexual qualities of middle aged male rats after dosing them with 0.5
g/kg of various fractions of E. longifolia whilst the control group received
3 ml/kg of normal saline daily for 12 weeks. Results showed than E.
longifolia Jack enhanced the sexual qualities of the middle aged male rats
by decreasing their hesitation time as compared to controls with various
fractions of E. longifolia Jack produced 865-916 (91-96), 860-914 (92-98),
850-904 (93-99), 854-890 (95-99), 844-880 (94-98), 840-875 (94-98), 830-870
(94-98), 825-860 (94-98), 820-850 (96-99), 800-840 (93-98), 750-795 (94-99)
and 650-754 sec (82-95%) in contrast to controls which produced 950 (100),
934 (100), 910 (100), 900 (100), 895 (100), 890 (100), 885 (100), 880 (100),
855 (100), 860 (100), 800 (100) and 790 sec (100%) throughout the
investigation period. Besides these, there was a transient increase in the %
of the male rats responding to the right choice after chronic administration
of 0.5 g/kg E. longifolia Jack, with more than 50% of the male rats scored
right choice after 2 weeks post-treatment and the effect was more prominent
at the dose of the observation period. However, there was no sexual
enhancement of the middle aged male rats which consumed normal saline since
only 45-55% of the male rats responded to right choice throughout the
investigation period. Hence, this study shows that E. longifolia Jack
enhanced the sexual qualities of the middle aged male rats, further supports
the folkuse of E. longifolia Jack as an aphrodisiac.
PMID: 13678248 [PubMed - indexed for MEDLINE]
Aphrodisiac evaluation in non-copulator male rats after
chronic administration of Eurycoma longifolia Jack.
School of Pharmaceutical Sciences, University of
Science Malaysia, Minden, 11800, Penang, Malaysia,
as reported in
Fundam
Clin Pharmacol. 2001 Aug;15(4):265-8.
The aphrodisiac effect of Eurycoma longifolia Jack (0.5
g/kg) was evaluated in noncopulator male rats using an electrical cage.
Fractions of E. longifolia Jack decreased the hesitation time of
noncopulator male rats, throughout the investigation period. Furthermore, it
possessed a transient increase in the percentage of the male rats responding
to the right choice, more than 50% of the male rats scored "right choice"
after 3 weeks post-treatment and the effect became more prominent after 8
weeks post-treatment (only 40-50% of the control male rats responded to the
right choice) using the electrical copulation cage. Hence, this study lends
further support to the use of the plant by indigenous populations as a
traditional medicine for its aphrodisiac property.
PMID: 11564133 [PubMed - indexed for MEDLINE]
Effects of Eurycoma longifolia jack on laevator ani
muscle in both uncastrated and testosterone-stimulated castrated intact male
rats.
School of Pharmaceutical Sciences, University Science
Malaysia, Minden, 11800, Penang, Malaysia.
hhang@usm.my, as reported in
Arch Pharm
Res. 2001 Oct;24(5):437-40
It has been reported that Eurycoma longifolia Jack
commonly known as Tongkat Ali has gained notoreity as a symbol of man's ego
and strength by the Malaysian men because it increases male virility and
sexual prowess during sexual activities. As such, the effects of 200, 400
and 800 mg/kg of butanol, methanol, water and chloroform fractions of E.
longifolia Jack were studied on the laevator ani muscle in both uncastrated
and testosterone-stimulated castrated intact male rats after dosing them for
12 consecutive weeks. Results showed that 800 mg/kg of butanol, methanol,
water and chloroform fractions of E. longifolia Jack significantly increased
(p<0.05) the leavator ani muscle to 58.56+/-1.22, 58.23+/-0.31, 60.21
+/-0.86 and 62.35 +/-0.98 mg/100 g body weight, respectively, when compared
with the control (untreated) in the uncastrated intact male rats and
49.23+/-0.82, 52.23+/-0.36, 50.21+/-0.66 and 52.35+/-0.58 mg/100 g body
weight, respectively, when compared to control (untreated) in the
testosterone-stimulated castrated intact male rats. Hence, the
pro-androgenic effect as shown by this study further supported the
traditional use of this plant as an aphrodisiac.
PMID: 11693547 [PubMed - indexed for MEDLINE]
Sexual arousal in sexually sluggish old male rats after
oral administration of Eurycoma longifolia Jack.
School of Pharmaceutical Sciences, University Science
Malaysia, Minden, Penang, Malaysia.
hhang@usm.my, as reported in
Basic Clin Physiol Pharmacol. 2004;15(3-4):303-9.
Eurycoma longifolia Jack commonly known as Tongkat Ali
in Malaysia, has been used in Malaysia to increase male virility and sexual
prowess. The objective of this study is to evaluate sexual arousal in
sexually sluggish old male rats, 24 months old and retired breeders,
receiving 200, 400, or 800 mg/kg of various fractions of E. longifolia Jack,
twice daily, for 10 days. Control rats received 3 ml/kg of normal saline.
The aphrodisiac effect was monitored by the act of yawning and stretching
because yawning, either alone or associated with stretching, is considered
an ancestral vestige surviving throughout evolution that promotes sexual
arousal. The results showed that 800 mg/kg of E. longifolia Jack increased
yawning by 50% and stretching by 16.7% in sexually sluggish old male rats,
by 676-719% and 31-336%, respectively, in sexually active male rats, and by
22-44% and 75-100%, respectively, in middle aged, 9 months old and retired
breeders. We conclude that the results of this study support the folk use of
this plant as an aphrodisiac.
PMID: 15803965 [PubMed - indexed for MEDLINE]
Tongkat ali
is also effective against germs
Antibacterial activity of Eurycoma longifolia Jack. A Malaysian medicinal
plant.
Saudi Med J. 2007 Sep;28(9):1422-1424. Farouk AE, Benafri A. Biomolecular
Engineering Research Unit, Department of Biotechnology Engineering,
Kulliyyah of Engineering, International Islamic University Malaysia, Jalan
Gombak, 53100, Kuala Lumpur, Malaysia.
To evaluate methanolic, ethanolic, acetone
and aqueous extracts from different parts of tongkat ali (leave, stem, and
root) for antibacterial activity against Gram-positive and Gram-negative
bacteria and to utilize the leaves and stem parts rather than the root,
which is already used for male sexual enhancement in Malaysia. The alcoholic
and acetone extracts from leaves and stems of tongkat alli contain potent
antibacterial agent(s). This plant can serve as a potential source of
antibacterial compounds.
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References: |
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1. Suong NN, Bhatnagar S, Polonsky J.
Structure of laurycolactone A and B, new
C18 - quassinoids from Eurycoma longifolia
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Iitaka Y. Highly oxygenated quassinoids
from Eurycoma longifolia. Phytochemistry.
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Biphenylneolignans from wood of Eurycoma
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H, Saito I, Sankawa U.
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quassinoid from Eurycoma longifolia.
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Noguchi H, Sankawa U.
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quassinoids from Eurycoma longifolia.
Phytochemistry. 1991;30(9): 3138-3141.
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Hiraga Y, Yamasaki K. Canthin-6-one and
beta-carboline alkaloids from Eurycoma
harmandiana. Phytochemistry.
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14. Chan KL, O’Neill MJ, Phillipson JD,
Warhurst DC. Plants as sources of
antimalarial drugs. Part 3. Eurycoma
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15. Choo CY, Chan KL. High performance
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canthinone alkaloids from Eurycoma
longifolia. Planta Medica.
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K. Cytotoxic quassinoids and tirucallane-type
triterpene from the woods of Eurycoma
longifolia. Chemical and Pharmaceutical
Bulletin. 1992;40:1053-1055.
17. Itokawa H, Kishi E, Morita H, Takeya
K, Iitaka Y. A new squalene-type
triterpene from the woods of Eurycoma
longifolia. Chemistry Letters.
1991;2221-2222.
18. Itokawa H, Kishi E, Morita H, Takeya
K, Iitaka Y. Eurylene, a new squalene-type
triterpene from Eurycoma longifolia.
Tetrahedron Letters.
1991;32(15):1803-1804.
19. Itokawa H, Qin X-R, Morita H, Takeya
K. Novel quassinoids from Eurycoma
longifolia. Chemical and Pharmaceutical
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Eurycoma longifolia as plant growth
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after chronic administration of Eurycoma
longifolia Jack. Fundamental and Clinical
Pharmacology. 2001;15(4):265-268.
25. Ang HH, Chan KL, Gan EK, Yuen KH.
Enhancement of sexual motivation in
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Clinical Pharmacology. 2002;16:479-483.
27. Ang HH, Cheang HS, Yusof AP. Effects
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Experimental Animal. 2000;49(1):35-38.
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H, Tanaka O. New quassinoids from the
roots of Eurycoma longifolia. Chemistry
Letters. 1990;749-752.
32. Itokawa H, Kishi E, Morita H, Takeya
K. Cytotoxic quassinoids and tirucallane-type
triterpene from the woods of Eurycoma
longifolia. Chemical and Pharmaceutical
Bulletin. 1992;40:1053-1055.
33. Tan S, Yuen KH, Chan KL. HPLC analysis
of plasma 9-methoxycanthin-6-one from
Eurycoma longifolia and its application in
a bioavailability/pharmacokinetic study.
Planta Medica. 2002;68:355-358.
34. Jiwajinda S, Santisopasri V, Murakami
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1991;26:345-349.
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How and Why Tongat Ali
is the Answer
to Male Erection Problems
Testosterone is the most important representative of the
male sex hormones collectively known as androgen produces by
the gonads. Its secretion stimulates the differentiation of
the male reproductive tract in the embryo, the decent of the
testes into the scrotum, the further development of the
reproductive tract and penis during puberty and maturation
of the sperm.
It is also responsible for the development of male secondary
sex characteristics such as moustache, beard, enlargement of
the larynx (deep voice) and increase production of the
sebaceous glands, Testosterone also play a role in the
development and maintenance of male libido (sexual desire)
and behavior.
Testosterone have other non sexual roles: It serves the
important function for protein biosynthesis in accelerating
muscle build-up, increases the formation of red blood cells,
speeds up regeneration and recovery time after illness or
injury. It stimulates the entire metabolic activity
especially in the energy metabolic pathways and burning
fats.
Research shows that during puberty. Their lifetime peak at
the age of 25 years old, and steadily decrease with age.
Some Clinical Studies indicate that generally on average,
testosterone levels drops as much as 2 % on yearly basis
after the age of 30 years old. At the age of 60 years old
the expected testosterone production is only 45-50%. A more
prominent decline was observed in individuals who are heavy
smokers and alcoholic.
Risk of low Testosterone
1) Osteoporosis and hip fracture
2) Heart disease and myocardial infarction
3) Stroke and cardiovascular disease
4) Prostate cancer
5) Senile dementia
Benefits of Testosterone
1) Stronger bones
2) Increase muscle mass
3) Decrease body fat
4) Increase metabolic rates and oxidative phosphorylation
5) Decrease stress
6) Improve brain function including memory
7) Improve sexual performance
Eurycoma L Jack
(Tongkat
Ali ) is a proven testosterone booster. This herb is
particularly reknown in Asia for its ability to increase
testosterone up to 440%. It achieves this by positively
affecting hormone balance to naturally stimulate the body to
produce more free testosterone.
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The highest grade of
Tongkat Ali extract, containing
mainly phenolic components, tannins,
high molecular weight polysaccharide,
glycoprotein and mucopolysacharides. It
is believed that these water soluble
components are biologically active in
rendering some of the observed
testosterone boosting and health
properties.
Tongkat Ali Powder extract is an
all-natural sexual stimulant engineered
to increase sexual stamina, arousal and
fertility. Unlike the competition. We
only use the highest-grade extracts and
nutriceuticals available.
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Tongkat Ali naturally incites the
testes to produce more testosterone on
their own by sending signal to the
hypothalamus and the pituitary glands,
and NOT by supplying exogenous
testosterone. Synthetic testosterone
(anabolic steroids) can supplement your
body with testosterone, but steroids
interfere awkwardly with male sexuality,
causing penile and testicular shrinkage.
When testosterone levels are elevated,
the sex hormones (androgensand
estrogens) will signal your body to
decrease or stop its own testosterone
production, this is call negative
feedback. Tongkat Ali intercepts the
negative feedback to the hypothalamus
and pituitary gland, which results in
the body to continuing to produce
testosterone at elevated levels. Because
the testes are in full testosterone
production mode, the penis and testicles
will increase in size.
Tongkat Ali acts through the
enhancement of testosterone and also c-GMP
production. As it enhances the synthesis
of the hormone it takes a longer time
period to exert its effect. The benefits
are felt gradually after a period of
time. Optimal effectiveness should be
felt within a week of continuous
uninterrupted use. When the testosterone
level increases, the heath and vitality
are restored.
Tongkat Ali does not act in the same
way as other claimed aphrodisiacs, which
take effect immediately. It has to be
consumed regularly over time. The mode
and mechanism of actions are different.
Optimum effectiveness results should be
felt within a week of continous
uninterupted use. Twice a day )
Tongkat Ali water soluble extract is
not a stimulant. Aphrodisiac effects of
< href="http://en.wikipedia.org/wiki/Tongkat_Ali">Tongkat
Ali varies depending on lifestyle and
also the physical and physiological
state of the individual.
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Water Soluble
Extract vs Others |
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Most, if not all,
Tongkat Ali products available in
the market today are pulverized
(sawdust) root. Poor and improper
extraction techniques.
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1. |
Until they are
scientifically analyzed in the
laboratory, there is no way to
verify which plant, plant roots or
plant parts are being used. |
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2. |
Beside, the raw
roots are fungus-prone. Unless
stringently quality controlled, even
grounded root in capsules can
deteriorate over time and are
subject to attack from fungi and
microorganism, |
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Which could cause
toxic and side effects over prolong
term usage which may damage the
liver and kidney. |
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4. |
Natural Powder are
only 1% soluble whereas our water
soluble extract is completely
soluble. |
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5. |
Most are not fully
tested with proven clinical trials
to prove their product safety and
efficacy. |
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Poor and irregular
quality standards. |
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7. |
The purest grade
contains the 1% active ingredients,
others do not have such purity and
may contain other impurities and
substances. |
We utilizing a
revolutionary extract process,
Tongkat Ali Water Soluble Extract
captures the pure essence of the herb,
offering 100%
Tongkat Ali in its definition form
Superior, Safe and Effective.
Stringent extraction and manufacturing
practice translates into superior
efficacy and quality standards. Product
that you would trust and deliver to your
clients with a peace of mind. [
Please check out our
production process ].
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In the study,
Tongkat Ali freeze dried aqueous
extract was orally administered as
multiple doses to mice at the dose of
3,500 mg/kg body weight.
CONCLUSION:
When tested
at the dose levels of 3,500 mg/kg
(equivalent to 3,500 doses) neither
caused death of the treated male and
female rats nor induced any signs of
intoxication during the observation
period of 28 days. Body weight gain was
not affected in treated rats throughout
the observation period of 10 days
following treatment and no gross
pathological alterations could be
detected in any of the male and female
rats at the termination of the study.
Based on these results, and as per the
interpretation criteria suggested by
guidelines of
WHO,
the test article the compound is
unlikely to posses hazardous substance
therefore safe to be used as herbal
preparation risk even at high doses.
Scientist and researchers have shown
that the water soluble extract is very
safe and non toxic, even at relative
high dosage.
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It was proven on
human and mice that after five days
dosage twice daily, there is an
increase in the testosterone level
of 440 % in human and 270 % in mice.
Dosage twice a day, benefits
generally accrue within 1 week.
After three weeks, marked
improvement in testosterone levels
occur in many |
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Testosterone is the
hormone that stimulates sexual
development in the male infant, bone and
muscle growth in adult males, and is
responsible for sexual drive. During
puberty, testosterone levels are at
their lifetime peak. They begin to
decline around the age of 23. This is
where testosterone therapy comes into
play. Many men and women suffer from the
lack of important hormones and
replacement therapy is simply the most
effective way to combat the signs of
aging.
Sex hormones like
"Estrogen and progesterone profoundly
affect the brain. The increasing memory
loss and mild mental confusion emerging
in middle age are largely due to
declining levels of estrogen and
progesterone in women. In men, these
same problems are caused by decreasing
testosterone and increasing estrogen
levels beginning in the late thirties or
early forties. Insomnia in women is also
related to a lack of estrogen."
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